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1

Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?

Coenye, Tom, Goeres, Darla, Van Bambeke, Françoise, Bjarnsholt, Thomas

Journal:

Clinical Microbiology and Infection

Année:

2018

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2018

2

The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase

Siala, Wafi, Kucharíková, Soňa, Braem, Annabel, Vleugels, Jef, Tulkens, Paul M, Mingeot-Leclercq, Marie-Paule, Van Dijck, Patrick, Van Bambeke, Françoise

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2016

3

Natural and hemi-synthetic pentacyclic triterpenes as antimicrobials and resistance modifying agents against Staphylococcus aureus: a review

Catteau, Lucy, Zhu, Li, Van Bambeke, Françoise, Quetin-Leclercq, Joëlle

Journal:

Phytochemistry Reviews

Année:

2018

Langue:

english

Fichier:

PDF, 8.59 MB

english, 2018

4

Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic

Sophie Denamur, Donatienne Tyteca, Jacqueline Marchand-Brynaert, Françoise Van Bambeke, Paul M. Tulkens, Pierre J. Courtoy, Marie-Paule Mingeot-Leclercq

Journal:

Free Radical Biology and Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2011

5

Gentamicin-induced apoptosis in LLC-PK1 cells: Involvement of lysosomes and mitochondria

Hélène Servais, Patrick Van Der Smissen, Gaëtan Thirion, Gauthier Van der Essen, Françoise Van Bambeke, Paul M. Tulkens, Marie-Paule Mingeot-Leclercq

Journal:

Toxicology and Applied Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 602 KB

english, 2005

6

Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages

Coralie M. Vallet, Béatrice Marquez, Eva Ngabirano, Sandrine Lemaire, Marie-Paule Mingeot-Leclercq, Paul M. Tulkens, Françoise Van Bambeke

Journal:

International Journal of Antimicrobial Agents

Année:

2011

Langue:

english

Fichier:

PDF, 659 KB

english, 2011

7

Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy

Van Bambeke, Françoise

Journal:

Future Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2015

8

Preliminary evidences of the direct and indirect antimicrobial activity of 12 plants used in traditional medicine in Africa

Catteau, Lucy, Van Bambeke, Françoise, Quetin-Leclercq, Joëlle

Journal:

Phytochemistry Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 562 KB

english, 2015

9

Optimizing β-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?

Delattre, Isabelle K., Taccone, Fabio S., Jacobs, Frédérique, Hites, Maya, Dugernier, Thierry, Spapen, Herbert, Laterre, Pierre-François, Wallemacq, Pierre E., Van Bambeke, Françoise, Tulkens, Paul M.

Journal:

Expert Review of Anti-infective Therapy

Année:

2017

Langue:

english

Fichier:

PDF, 827 KB

english, 2017

10

Loss of activity of ceftazidime-avibactam due to Mex-AB-OprM efflux and overproduction of AmpC cephalosporinase in Pseudomonas aeruginosa isolated from patients suffering from cystic fibrosis

Chalhoub, Hussein, Sáenz, Yolanda, Nichols, Wright W., Tulkens, Paul M., Van Bambeke, Françoise

Journal:

International Journal of Antimicrobial Agents

Année:

2018

Langue:

english

Fichier:

PDF, 620 KB

english, 2018

11

Antibiotic Resistance, Biofilm Formation, and Intracellular Survival As Possible Determinants of Persistent or Recurrent Infections by Staphylococcus aureus in a Vietnamese Tertiary Hospital: Focus on Bacterial Response to Moxifloxacin

Nguyen, Tiep Khac, Argudín, Maria A., Deplano, Ariane, Nhung, Pham Hong, Nguyen, Hoang Anh, Tulkens, Paul M., Dodemont, Magali, Van Bambeke, Françoise

Journal:

Microbial Drug Resistance

Année:

2019

Fichier:

PDF, 247 KB

2019

12

Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity

Carlo Franchini, Marilena Muraglia, Filomena Corbo, Marco Antonio Florio, Antonia Di Mola, Antonio Rosato, Rosanna Matucci, Marta Nesi, Francoise van Bambeke, Cesare Vitali

Journal:

Archiv der Pharmazie

Année:

2009

Langue:

english

Fichier:

PDF, 475 KB

english, 2009

13

ChemInform Abstract: Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity.

Carlo Franchini, Marilena Muraglia, Filomena Corbo, Marco Antonio Florio, Antonia Di Mola, Antonio Rosato, Rosanna Matucci, Marta Nesi, Francoise van Bambeke, Cesare Vitali

Journal:

Année:

2010

Fichier:

PDF, 21 KB

2010

14

Aminoglycoside antibiotics prevent the formation of non-bilayer structures in negatively-charged membranes. Comparative studies using fusogenic (bis(β-diethylaminoethylether)hexestrol) and aggregating (spermine) agents

Françoise van Bambeke, Marie-Paule Mingeot-Leclercq, Robert Brasseur, Paul M. Tulkens, André Schanck

Journal:

Chemistry and Physics of Lipids

Année:

1996

Langue:

english

Fichier:

PDF, 942 KB

english, 1996

15

Modulation of the in vitro activity of lysosomal phospholipase A1 by membrane lipids

Jocelyne Piret, André Schanck, Sylvie Delfosse, Françoise Van Bambeke, Bellamkonda K. Kishore, Paul M. Tulkens, Marie-Paule Mingeot-Leclercq

Journal:

Chemistry and Physics of Lipids

Année:

2005

Langue:

english

Fichier:

PDF, 189 KB

english, 2005

16

Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus

Marie-Paule Mingeot-Leclercq, Laurence Lins, Mariam Bensliman, Françoise Van Bambeke, Patrick Van Der Smissen, Jacques Peuvot, André Schanck, Robert Brasseur

Journal:

Chemistry and Physics of Lipids

Année:

2002

Langue:

english

Fichier:

PDF, 385 KB

english, 2002

17

Molecular models of human P-glycoprotein in two different catalytic states

Jean-Paul Becker, Grégoire Depret, Françoise Van Bambeke, Paul M Tulkens, Martine Prévost

Journal:

BMC Structural Biology

Année:

2009

Langue:

english

Fichier:

PDF, 3.23 MB

english, 2009

18

Penicillin-binding Proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity ofListeria monocytogenes

Sébastien Van de Velde, Stéphane Carryn, Françoise Van Bambeke, Colin Hill, Paul M Tulkens, Roy D Sleator

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 640 KB

english, 2009

19

Isolation and 2-D-DIGE proteomic analysis of intracellular and extracellular forms of Listeria monocytogenes

Sébastien Van de Velde, Edouard Delaive, Marc Dieu, Stéphane Carryn, Françoise Van Bambeke, Bart Devreese, Martine Raes, Paul M. Tulkens

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 351 KB

english, 2009

20

Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: Insight into the mechanism of ligand migration and binding sites

Stéphane Vandevuer, Françoise Van Bambeke, Paul M. Tulkens, Martine Prévost

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2006

Langue:

english

Fichier:

PDF, 831 KB

english, 2006

21

Structure-Based Design of Benzoxazoles as new Inhibitors for D-Alanyl – D-Alanine Ligase

Isabelle Tytgat, Stéphane Vandevuer, Isabelle Ortmans, Finton Sirockin, Evelina Colacino, Françoise Van Bambeke, Colette Duez, Jacques H. Poupaert, Paul M. Tulkens, Annick Dejaegere, Martine Prévost

Journal:

Molecular Informatics

Année:

2009

Langue:

english

Fichier:

PDF, 513 KB

english, 2009

22

Alterations in membrane permeability induced by aminoglycoside antibiotics: studies on liposomes and cultured cells

Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq, André Schanck, Robert Brasseur, Paul M. Tulkens

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1993

23

Aminoglycoside antibiotics induce aggregation but not fusion of negatively-charged liposomes

Françoise Van Bambeke, Paul M. Tulkens, Robert Brasseur, Marie-Paule Mingeot-Leclercq

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1995

24

Cocaine induces a mixed lysosomal lipidosis in cultured fibroblasts, by inactivation of acid sphingomyelinase and inhibition of phospholipase A1

Marie-Cécile Nassogne, Chantal Lizarraga, Francisca N'Kuli, Françoise Van Bambeke, Roger Van Binst, Pierre Wallemacq, Paul M Tulkens, Marie-Paule Mingeot-Leclercq, Thierry Levade, Pierre J Courtoy

Journal:

Toxicology and Applied Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 396 KB

english, 2004

25

Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin

Coralie M. Vallet, Béatrice Marquez, Naïma Nhiri, Ahalieyah Anantharajah, Marie-Paule Mingeot-Leclercq, Paul M. Tulkens, Jean-Yves Lallemand, Eric Jacquet, Françoise Van Bambeke

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 579 KB

english, 2011

26

Antibiotic efflux pumps

Françoise Van Bambeke, Elisabetta Balzi, Paul M Tulkens

Journal:

Biochemical Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 488 KB

english, 2000

27

Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts

Donatienne Tyteca, Patrick Van Der Smissen, Françoise Van Bambeke, Karin Leys, Paul M. Tulkens, Pierre J. Courtoy, Marie-Paule Mingeot-Leclercq

Journal:

European Journal of Cell Biology

Année:

2001

Langue:

english

Fichier:

PDF, 259 KB

english, 2001

28

Azithromycin, a Lysosomotropic Antibiotic, Has Distinct Effects on Fluid-Phase and Receptor-Mediated Endocytosis, but Does Not Impair Phagocytosis in J774 Macrophages

Donatienne Tyteca, Patrick Van Der Smissen, Marcel Mettlen, Françoise Van Bambeke, Paul M. Tulkens, Marie-Paule Mingeot-Leclercq, Pierre J. Courtoy

Journal:

Experimental Cell Research

Année:

2002

Langue:

english

Fichier:

PDF, 446 KB

english, 2002

29

Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation

Cécile Gerbaux, Françoise Van Bambeke, Jean-Pierre Montenez, Jocelyne Piret, Grégory Morlighem, Paul M. Tulkens

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 376 KB

english, 1996

30

Interactions of ciprofloxacin with DPPC and DPPG: Fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis

Hayet Bensikaddour, Karim Snoussi, Laurence Lins, Françoise Van Bambeke, Paul M. Tulkens, Robert Brasseur, Erik Goormaghtigh, Marie-Paule Mingeot-Leclercq

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2008

Langue:

english

Fichier:

PDF, 713 KB

english, 2008

31

Interactions of oritavancin, a new lipoglycopeptide derived from vancomycin, with phospholipid bilayers: Effect on membrane permeability and nanoscale lipid membrane organization

Oscar Domenech, Grégory Francius, Paul M. Tulkens, Françoise Van Bambeke, Yves Dufrêne, Marie-Paule Mingeot-Leclercq

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2009

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2009

32

Interactions of oritavancin, a new semi-synthetic lipoglycopeptide, with lipids extracted from Staphylococcus aureus

Oscar Domenech, Yves F. Dufrêne, Françoise Van Bambeke, Paul M. Tukens, Marie-Paule Mingeot-Leclercq

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2010

Langue:

english

Fichier:

PDF, 993 KB

english, 2010

33

Glycopeptides in clinical development: pharmacological profile and clinical perspectives

Françoise Van Bambeke

Journal:

Current Opinion in Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 165 KB

english, 2004

34

The bacterial envelope as a target for novel anti-MRSA antibiotics

Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq, Marc J. Struelens, Paul M. Tulkens

Journal:

Trends in Pharmacological Sciences

Année:

2008

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2008

35

Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Aβ C-terminal fragment

Marie-Paule Mingeot-Leclercq, Laurence Lins, Mariam Bensliman, Annick Thomas, Françoise Van Bambeke, Jacques Peuvot, André Schanck, Robert Brasseur

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2003

Langue:

english

Fichier:

PDF, 277 KB

english, 2003

36

Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity

Françoise Van Bambeke, Jean-Pierre Montenez, Jocelyne Piret, Paul M. Tulkens, Pierre J. Courtoy, Marie-Paule Mingeot-Leclercq

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1996

37

Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies

Jean-Pierre Montenez, Françoise Van Bambeke, Jocelyne Piret, André Schanck, Robert Brasseur, Paul M. Tulkens, Marie-Paule Mingeot-Leclercq

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1.22 MB

english, 1996

38

Activity of finafloxacin, a novel fluoroquinolone with increased activity at acid pH, towards extracellular and intracellular Staphylococcus aureus, Listeria monocytogenes and Legionella pneumophila

Sandrine Lemaire, Françoise Van Bambeke, Paul M. Tulkens

Journal:

International Journal of Antimicrobial Agents

Année:

2011

Langue:

english

Fichier:

PDF, 335 KB

english, 2011

39

Safety Profile of the Respiratory Fluoroquinolone Moxifloxacin

Professor Françoise Van Bambeke, Paul M. Tulkens

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 358 KB

english, 2009

40

Glycopeptide Antibiotics

Dr Françoise Van Bambeke, Yves Van Laethem, Patrice Courvalin, Paul M. Tulkens

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 590 KB

english, 2004

41

2-Aminobenzothiazole derivatives: Search for new antifungal agents

Catalano, Alessia, Carocci, Alessia, Defrenza, Ivana, Muraglia, Marilena, Carrieri, Antonio, Van Bambeke, Françoise, Rosato, Antonio, Corbo, Filomena, Franchini, Carlo

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 720 KB

english, 2013

42

Multidrug-Resistant Streptococcus pneumoniae Infections

Dr Françoise Van Bambeke, René R. Reinert, Peter C. Appelbaum, Paul M. Tulkens…

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 215 KB

english, 2007

43

Development and validation of a high performance liquid chromatography assay for the determination of temocillin in serum of haemodialysis patients

Miranda Bastos, Ana C., Vandecasteele, Stefaan J., Tulkens, Paul M., Spinewine, Anne, Van Bambeke, Françoise

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2014

Langue:

english

Fichier:

PDF, 541 KB

english, 2014

44

Pharmacological Characterization of 7-(4-(Piperazin-1-yl)) Ciprofloxacin Derivatives: Antibacterial Activity, Cellular Accumulation, Susceptibility to Efflux Transporters, and Intracellular Activity

Marquez, Béatrice, Pourcelle, Vincent, Vallet, Coralie M., Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M., Marchand-Bruynaert, Jacqueline, Van Bambeke, Françoise

Journal:

Pharmaceutical Research

Année:

2014

Langue:

english

Fichier:

PDF, 421 KB

english, 2014

45

Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections

Van Bambeke, Françoise, Harms, Joerg M, Van Laethem, Yves, Tulkens, Paul M

Journal:

Expert Opinion on Pharmacotherapy

Année:

2008

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2008

46

Renaissance of antibiotics against difficult infections: Focus on oritavancin and new ketolides and quinolones

Van Bambeke, Françoise

Journal:

Annals of Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 567 KB

english, 2014

47

Validation of a HPLC-MS/MS assay for the determination of total and unbound concentration of temocillin in human serum

Ngougni Pokem, Perrin, Miranda Bastos, Ana C., Tulkens, Paul M., Wallemacq, Pierre, Van Bambeke, Françoise, Capron, Arnaud

Journal:

Clinical Biochemistry

Année:

2015

Langue:

english

Fichier:

PDF, 509 KB

english, 2015

48

Role of rsbU and Staphyloxanthin in Phagocytosis and Intracellular Growth of Staphylococcus aureus in Human Macrophages and Endothelial Cells

Olivier, Aurélie C., Lemaire, Sandrine, Van Bambeke, Françoise, Tulkens, Paul M., Oldfield, Eric

Journal:

The Journal of Infectious Diseases

Année:

2009

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2009

49

Impairment of Growth of Listeria monocytogenes in THP‐1 Macrophages by Granulocyte Macrophage Colony‐Stimulating Factor: Release of Tumor Necrosis Factor–α and Nitric Oxide

Carryn, Stéphane, Van de Velde, Sébastien, Van Bambeke, Françoise, Mingeot‐Leclercq, Marie‐Paule, Tulkens, Paul M.

Journal:

The Journal of Infectious Diseases

Année:

2004

Langue:

english

Fichier:

PDF, 223 KB

english, 2004

50

Activities of Antibiotic Combinations against Resistant Strains of Pseudomonas aeruginosa in a Model of Infected THP-1 Monocytes

Buyck, Julien M., Tulkens, Paul M., Van Bambeke, Françoise

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2015